Combined Universities Brain Imaging Centre, UK.
Exp Brain Res. 2010 May;203(1):193-204. doi: 10.1007/s00221-010-2225-3. Epub 2010 Mar 25.
Selective attention is popularly assessed with colour Stroop tasks in which participants name the ink colour of colour words, whilst resisting interference from the natural tendency to read the words. Prior studies hinted that the key brain regions (dorsolateral prefrontal (dlPFC) and anterior cingulate cortex (ACC)) may vary their degree of involvement, dependent on attentional demand. This study aimed to determine whether a parametrically varied increase in attentional demand resulted in linearly increased activity in these regions, and/or whether additional regions would be recruited during high attentional demand. Twenty-eight healthy young adults underwent fMRI whilst naming the font colour of colour words. Linear increases in BOLD response were assessed with increasing percentage incongruent trials per block (0, 20, 40, 60, 80, and 100%). Whilst ACC activation increased linearly according to incongruity level, dlPFC activity appeared constant. Together with behavioural evidence of reduced Stroop interference, these data support a load-dependent conflict-related response in ACC, but not dlPFC.
选择性注意通常通过颜色斯特鲁普任务进行评估，参与者需要命名颜色词的墨迹颜色，同时抵制阅读这些词的自然倾向的干扰。先前的研究表明，关键的大脑区域（背外侧前额叶皮层（dlPFC）和前扣带皮层（ACC））可能会根据注意力的需求改变其参与程度。本研究旨在确定注意力需求的参数变化是否会导致这些区域的活动呈线性增加，以及/或者在高注意力需求时是否会招募其他区域。28 名健康的年轻成年人在进行 fMRI 时，需要说出颜色词的字体颜色。通过增加每个块的不一致试验的百分比（0、20、40、60、80 和 100%）来评估 BOLD 反应的线性增加。虽然 ACC 的激活根据不一致性水平呈线性增加，但 dlPFC 的活动似乎是恒定的。结合行为学上的 Stroop 干扰减少的证据，这些数据支持 ACC 中与负荷相关的冲突反应，但 dlPFC 则不然。
