Kihara M, Umemura S, Takagi N, Hirawa N, Minamisawa K, Matsukawa T, Miyajima E, Shionoiri H, Ishii M
Second Department of Internal Medicine, Yokohama City University School of Medicine, Japan.
Klin Wochenschr. 1991 Mar 18;69(5):228-31. doi: 10.1007/BF01646948.
A case is presented in which suprarenal neurilemoma was associated with paroxysmal attacks of hypertension, headache and sweating with elevated plasma and urinary catecholamines. Pheochromocytoma was excluded using an overnight clonidine suppression test. Ultrasonography, computed tomography and magnetic resonance imaging, which showed cystic mass with a pedicle continuing to the widened intervertebral foramen, were helpful for the preoperative diagnosis of retroperitoneal neurilemoma. The excised tumor was revealed to be benign neurilemoma and contain detectable levels of adrenaline, noradrenaline and dopamine. The relationships between tumor catecholamines and clinical manifestations will be discussed.
本文报告一例肾上腺神经鞘瘤,伴有阵发性高血压、头痛和出汗,血浆和尿儿茶酚胺升高。通过隔夜可乐定抑制试验排除了嗜铬细胞瘤。超声、计算机断层扫描和磁共振成像显示囊性肿块,有一蒂延续至增宽的椎间孔,有助于术前诊断腹膜后神经鞘瘤。切除的肿瘤为良性神经鞘瘤,含有可检测水平的肾上腺素、去甲肾上腺素和多巴胺。将讨论肿瘤儿茶酚胺与临床表现之间的关系。