等待肝移植患者的认知表现和情绪及其与终末期肝病模型的关系
Cognitive performance and mood in patients on the waiting list for liver transplantation and their relation to the model for end-stage liver disease.
作者信息
Miotto Eliane C, Campanholo Karina R, Machado Melissa A R, Benute Glaucia G R, Lucia Mara C S, Fráguas Renério, Bacchella Telesforo, Machado Marcel C C
机构信息
Division of Psychology and Liver Transplant Service of the Hospital das Clínicas, University of São Paulo Medical School, São Paulo, SP, Brazil.
出版信息
Arq Neuropsiquiatr. 2010 Feb;68(1):62-6. doi: 10.1590/s0004-282x2010000100014.
OBJECTIVE
To investigate the links between depression and cognitive functioning in patients with Hepatitis C and other chronic liver diseases with and without the use of alcohol on the waiting list for liver transplantation and their associations with the MELD classification.
METHOD
40 patients were evaluated on a waiting list for liver transplant by a battery of neuropsychological tests, depression scales and interview at the Liver Transplant Service, of the Hospital das Clínicas University of São Paulo Medical School.
RESULTS
After splitting the sample according to the education, the results showed statistical significance in the comparisons between groups of MELD > 15 and <15 in the following functions: estimated IQ, visual-spatial delayed recall and recognition as part of episodic memory and short term memory.
CONCLUSION
These findings, usually found in hepatic encephalopathy, corroborated with the literature and emphasized the need to investigate in more detail the cognitive functions of these patients in order to facilitate the adoption of different conducts.
目的
研究丙型肝炎及其他慢性肝病患者在等待肝移植期间，无论是否饮酒，其抑郁与认知功能之间的联系，以及它们与终末期肝病模型（MELD）分类的关联。
方法
圣保罗大学医学院临床医院肝脏移植科对40名等待肝移植的患者进行了一系列神经心理学测试、抑郁量表评估及访谈。
结果
根据教育程度对样本进行分组后，结果显示，在以下功能方面，MELD评分>15和<15的组间比较具有统计学意义：估计智商、视觉空间延迟回忆和识别（作为情景记忆和短期记忆的一部分）。
结论
这些通常在肝性脑病中发现的结果与文献相符，并强调需要更详细地研究这些患者的认知功能，以便采取不同的治疗措施。
Zotero 插件