Brau Beltrán J, Pericas Raventós R, López Valeiras L, Virto Barrio J L, Prats Pastor G, Verger Garau G
Unitat de Malalties Infeccioses, Hospital de la Santa Creu i Sant Pau, Barcelona.
Med Clin (Barc). 1991 Feb 9;96(5):161-4.
The aim of the study was to assess the number of urinary tract infections, the time between catheterization and the development of bacteriuria, the route taken by the microorganisms and the clinical relevance of infection in patients with bladder catheterization during a short time.
83 patients were evaluated by urine culture from the bladder, urethra, the connection of the catheter and the collecting system, and the collecting bag, on a daily basis during the 5 initial days, with clinical and microbiological follow up to 7 days after the removal of the catheter.
32% of patients developed bacteriuria. The mean interval between catheterization and the development of bacteriuria was 4.1 days. 45% of them were detected within 48 hours after catheter insertion. In 50% the causative organisms were detected in the urethra at least 24 hours previously. In no case the microorganism isolated from the connection between the catheter and the collecting system was subsequently isolated form bladder urine. Bacteriuria disappeared spontaneously in 27% of cases. Antibiotic therapy was necessary in 42%.
In the study population most urinary infections were due to previous urethral colonization and subsequent dragging into the bladder, in many cases at the same time of catheterization. A non-negligible number of bacteriurias disappeared spontaneously.
本研究的目的是评估短期留置导尿管患者的尿路感染数量、导尿与菌尿发生之间的时间、微生物的传播途径以及感染的临床相关性。
在最初5天内，每天对83例患者的膀胱、尿道、导尿管与集尿系统连接处以及集尿袋进行尿培养评估，并在拔除导尿管后进行7天的临床和微生物学随访。
32%的患者发生了菌尿。导尿与菌尿发生之间的平均间隔为4.1天。其中45%在导尿后48小时内被检测到。50%的患者在至少24小时前尿道中检测到病原菌。从导尿管与集尿系统连接处分离出的微生物，在随后的膀胱尿液中均未分离到。27%的病例菌尿自行消失。42%的病例需要抗生素治疗。
在本研究人群中，大多数尿路感染是由于先前尿道定植菌随后进入膀胱，在许多情况下与导尿同时发生。相当数量的菌尿会自行消失。
