Tüzer Erkut, Bilgin Zahide, Oter Kerem, Erçin Süleyman, Tinar Recep
Istanbul Univ Veteriner Fakültesi, Parazitoloji Anabilim Dali, Türkiye.
Turkiye Parazitol Derg. 2010;34(1):17-20.
Praziquantel, which has been used in the treatment and control of canine and feline tapeworm infections for about 35 years, has not been tested against these parasites for a long period in Turkey. This study was performed to evaluate the current efficacy of praziquantel against dog and cat tapeworms. Praziquantel injectable solution was administered to 26 dogs (14 of them were infected with Dipylidium caninum, 8 with Taenia spp and 2 with Echinococcus granulosus, 2 with both Dipylidium caninum and Taenia spp) and 2 cats (infected with Joyeuxiella pasqualei) subcutaneously at a dose of 0.1 ml/kg (5.68 mg active ingredient/kg). After treatment, animals were put in individual cages and their feces were taken daily for examination. Feces were examined macroscopically for tapeworm segments and scolexes and microscopically for tapeworm eggs by Fülleborn's flotation and Teleman's sedimentation (for fatty stools). To confirm results of analysis the examinations after treatment were repeated until two subsequent fecal analyses were negative. The parasites disappeared from the feces of all infected animals in 2 or 3 days after the treatment and the drug was found to be 100% effective against both dog and cat tapeworms. No adverse reactions were observed in both dogs and cats treated.
吡喹酮用于犬猫绦虫感染的治疗和控制已有约35年,但在土耳其尚未对这些寄生虫进行长期测试。本研究旨在评估吡喹酮对犬猫绦虫的当前疗效。将吡喹酮注射液以0.1 ml/kg(5.68 mg活性成分/kg)的剂量皮下注射给26只犬(其中14只感染犬复孔绦虫,8只感染带绦虫属,2只感染细粒棘球绦虫,2只同时感染犬复孔绦虫和带绦虫属)和2只猫(感染帕斯夸莱氏乔伊绦虫)。治疗后,将动物置于单独的笼子中,每天采集粪便进行检查。粪便通过富勒伯恩浮选法和特勒曼沉淀法(用于脂肪性粪便)进行宏观检查以查找绦虫节片和头节,并进行微观检查以查找绦虫卵。为确认分析结果,治疗后的检查重复进行,直到连续两次粪便分析呈阴性。治疗后2至3天,所有感染动物粪便中的寄生虫消失,发现该药物对犬猫绦虫均有100%的疗效。在接受治疗的犬猫中均未观察到不良反应。