Schomacker K T, Domankevitz Y, Flotte T J, Deutsch T F
Wellman Laboratories of Photomedicine, Department of Dermatology, Massachusetts General Hospital, Boston 02114.
Lasers Surg Med. 1991;11(2):141-51. doi: 10.1002/lsm.1900110208.
The wavelength dependence of the ablation threshold of a variety of tissues has been studied by using a tunable pulsed Co:MgF2 laser to determine how closely it tracks the optical absorption length of water. The Co:MgF2 laser was tuned between 1.81 and 2.14 microns, a wavelength region in which the absorption length varies by a decade. For soft tissues the ablation threshold tracks the optical absorption length; for bone there is little wavelength dependence, consistent with the low water content of bone. Thermal damage vs. wavelength was also studied for cornea and bone. Thermal damage to cornea has a weak wavelength dependence, while that to bone shows little wavelength dependence. Framing-camera pictures of the ablation of both cornea and liver show explosive removal of material, but differ as to the nature of the explosion.
通过使用可调谐脉冲钴镁氟化物（Co:MgF₂）激光器，研究了多种组织的消融阈值与波长的关系，以确定其与水的光吸收长度的接近程度。Co:MgF₂激光器的波长在1.81至2.14微米之间调谐，在该波长区域内，吸收长度变化了一个数量级。对于软组织，消融阈值跟踪光吸收长度；对于骨骼，波长依赖性很小，这与骨骼的低含水量一致。还研究了角膜和骨骼的热损伤与波长的关系。角膜的热损伤具有较弱的波长依赖性，而骨骼的热损伤则几乎没有波长依赖性。角膜和肝脏消融的分幅相机图片显示材料的爆炸性去除，但爆炸的性质有所不同。
