Goldobenko G V, Matveev B P, Shipilov V I, Klimakov B D, Tkachev S I
Med Radiol (Mosk). 1991;36(5):14-6.
The paper is devoted to a follow-up of 177 bladder cancer patients. The problems of providing radiotherapy with the use of hyperfractionation of a radiation dose were discussed. Despite an increase in a tumor dose by 15%, no increase in the number and expression of local radiation reactions is observed. Enhanced therapeutic efficacy was observed, particularly in cases of locally advanced tumors (T3). Three years after conventional radiotherapy 44% of the patients were alive, after hyperfractionated irradiation--69%.
该论文致力于对177例膀胱癌患者进行随访。讨论了使用超分割放射剂量进行放射治疗的问题。尽管肿瘤剂量增加了15%,但局部放射反应的数量和表现并未增加。观察到治疗效果增强,尤其是在局部晚期肿瘤(T3)的病例中。常规放疗三年后,44%的患者存活,超分割照射后为69%。