Lean T H, Vengadasalam D, Pachauri S, Miller E R
Int J Gynaecol Obstet. 1976;14(6):481-6. doi: 10.1002/j.1879-3479.1976.tb00089.x.
In a study of techniques for first trimester abortion conducted at Kandang Kerbau Hospital in Singapore from September 1973 to April 1975, 420 physically healthy gravidas were randomly assigned to one of two treatment groups either by D & C or vacuum aspiration. Half of the patients in each group were 6 to 10 menstrual weeks' gestation and half were 11 to 12 week's gestation. The numbers of women with one or more complications were the same for the two treatment groups, but were significantly less when termination was carried out at 11 to 12 weeks' gestation. Estimated blood loss was significantly lower for patients treated by VA (32.3 ml) than for patients treated by D & C (39.0 ml) at 6 to 10 week's gestation, but the difference in blood loss was not statistically significant at 11 to 12 weeks' gestation. Time from insertion to removal of the speculum was significantly less with VA than D & C at 6 to 10 weeks' gestation but not at 11 to 12 weeks' gestation. Since vacuum aspiration is at least as safe as D & C, and appears to be more convenient and costeffective, it should on the basis of this experience be accepted over D & C as the standard method for treatment of first trimester abortion.
1973年9月至1975年4月在新加坡康当葛宝医院进行的一项关于孕早期流产技术的研究中，420名身体健康的孕妇被随机分为两个治疗组，分别接受刮宫术或真空吸引术。每组中一半患者妊娠6至10周，另一半妊娠11至12周。两个治疗组出现一种或多种并发症的女性人数相同，但在妊娠11至12周时进行终止妊娠时并发症明显较少。在妊娠6至10周时，接受真空吸引术治疗的患者估计失血量（32.3毫升）明显低于接受刮宫术治疗的患者（39.0毫升），但在妊娠11至12周时失血量差异无统计学意义。在妊娠6至10周时，从插入窥器到取出窥器的时间，真空吸引术明显短于刮宫术，但在妊娠11至12周时并非如此。由于真空吸引术至少与刮宫术一样安全，而且似乎更方便且成本效益更高，基于此经验，它应被接受作为孕早期流产治疗的标准方法，取代刮宫术。
