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药物流产与手术真空吸引术的比较:女性对治疗的偏好与可接受性

Comparison of medical abortion with surgical vacuum aspiration: women's preferences and acceptability of treatment.

作者信息

Henshaw R C, Naji S A, Russell I T, Templeton A A

机构信息

Department of Obstetrics and Gynaecology, Aberdeen Maternity Hospital.

出版信息

BMJ. 1993 Sep 18;307(6906):714-7. doi: 10.1136/bmj.307.6906.714.

Abstract

OBJECTIVES

To assess women's preferences for, and the acceptability of, medical abortion and vacuum aspiration in the early first trimester.

DESIGN

Patient centred, partially randomised trial. Medical abortion was performed with mifepristone 600 mg followed 48 hours later by gemeprost 1 mg vaginal pessary. Vacuum aspiration was performed under general anaesthesia.

SETTING

Teaching hospital in Scotland.

PATIENTS

363 women undergoing legal induced abortion at less than nine weeks' gestation.

MAIN OUTCOME MEASURES

Women's preferences for method of abortion before abortion; acceptability judged two weeks after abortion by recording the method women would opt to undergo in future and by semantic differential rating technique.

RESULTS

73 (20%) women preferred to undergo medical abortion, and 95 (26%) vacuum aspiration; 195 (54%) were willing to undergo either method, and were allocated at random. Both procedures were highly acceptable to women with preferences. Gestation had a definite effect on acceptability in randomised women; at less than 50 days there were no differences, but between 50 and 63 days vacuum aspiration was significantly more acceptable.

CONCLUSIONS

Women who wish to use a particular method should be allowed their choice, regardless of gestation. Women of 50-63 days' gestation without preferences for a particular method are likely to find vacuum aspiration more acceptable. A patient centred, partially randomised trial design may be a useful tool in pragmatic research.

摘要

目的

评估妊娠早期头三个月内女性对药物流产和负压吸引术的偏好及可接受性。

设计

以患者为中心的部分随机试验。药物流产采用600毫克米非司酮,48小时后使用1毫克阴道前列腺素E1栓。负压吸引术在全身麻醉下进行。

地点

苏格兰的教学医院。

患者

363名妊娠少于9周且接受合法人工流产的女性。

主要观察指标

流产前女性对流产方式的偏好;流产两周后通过记录女性未来会选择接受的方式以及语义差异评分技术来判断可接受性。

结果

73名(20%)女性倾向于接受药物流产,95名(26%)倾向于负压吸引术;195名(54%)愿意接受任何一种方式,并被随机分配。两种手术方式对于有偏好的女性都具有很高的可接受性。妊娠时间对随机分组女性的可接受性有明确影响;妊娠少于50天时没有差异,但在50至63天之间,负压吸引术的可接受性明显更高。

结论

无论妊娠时间如何,应允许希望采用特定方式的女性进行选择。妊娠50至63天且对特定方式无偏好的女性可能会发现负压吸引术更易接受。以患者为中心的部分随机试验设计可能是实用研究中的一种有用工具。

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