Bieszczad M, Ejma M, Podemski R
Katedry i Kliniki Neurologii AM we Wrocławiu.
Neurol Neurochir Pol. 1991 Jan-Feb;25(1):7-14.
In 21 patients with parkinsonism and 20 healthy controls visual potentials evoked with checker pattern used as an alternating stimulus were studied. The left and right eye were examined separately recording visual cortical responses in the central occipital area. The analysed elements included the latency of the first highest positive wave P100 and the amplitude of the P100/N120 complex. Prolongation of the mean latency of P100 was found in patients with parkinsonism, but it was not significant statistically. No differences were found of the P100/N120 amplitude in the group with parkinsonism in relation to healthy controls. In the patients with parkinsonian syndrome (mainly of atherosclerotic origin) the mean latency of the visual potentials was longer and the amplitude was lower than in cases of Parkinson's disease. Attention is called to the high variability of the visual evoked potentials related to the clinical state and origin of the disease (parkinsonian syndrome and Parkinson's disease).
对21例帕金森病患者和20名健康对照者进行了研究,使用棋盘格模式作为交替刺激诱发视觉诱发电位。分别检查左眼和右眼,记录枕叶中央区的视觉皮层反应。分析的指标包括首个最高正向波P100的潜伏期以及P100/N120复合波的波幅。帕金森病患者中发现P100平均潜伏期延长,但在统计学上不显著。帕金森病组与健康对照组相比,P100/N120波幅未发现差异。在帕金森综合征(主要为动脉粥样硬化源性)患者中,视觉诱发电位的平均潜伏期更长,波幅低于帕金森病患者。需注意与疾病(帕金森综合征和帕金森病)的临床状态及病因相关的视觉诱发电位具有高度变异性。