Li Qian-qian, Liu Xiao-qin, Chen Xi-ping
Department of Forensic Medicine, Medical College of Soochow University, Suzhou 215123, China.
Fa Yi Xue Za Zhi. 2011 Apr;27(2):91-3, 101.
To explore pattern reversal visual evoked potential (PRVEP) P100 components in the patients with different visual acuity and the correlation of P100 components with visual acuity using different visual simulation angles.
PRVEPs were recorded at Oz point in the patients (100 eyes) with different visual acuity including 0.2, 0.4, 0.6, 0.8 and 1.0 and induced by pattern reversal visual simulation with the different spatial frequencies(check sizes: 8 degrees-7.5'). The latency and amplitude of components P100 were analyzed and statistical analysis was performed using SPSS 13.0 software.
The latency and amplitude of P100 wave showed a curvilinear relationship with check sizes. With check size 10 simulation in 0.2 visual acuity group, the P100 latency reached to the minimum and the P100 amplitude showed peak value. Other groups displayed the best value with check size 30'. The P100 latency and amplitude showed a linear correlation with visual acuity. With the increase of visual acuity, the P100 wave latency decreased and the amplitude increased gradually. Regression models between visual acuity and the Pic wave latency and amplitude were also established.
The regression functions can be an objective and accurate method to evaluate the visual acuity based on the better simulation angles using PRVEP examination.
探讨不同视力患者的图形翻转视觉诱发电位（PRVEP）P100成分，以及使用不同视觉模拟角度时P100成分与视力的相关性。
对视力分别为0.2、0.4、0.6、0.8和1.0的患者（100只眼）在Oz点记录PRVEP，采用不同空间频率（检查尺寸：8度 - 7.5'）的图形翻转视觉模拟进行诱发。分析P100成分的潜伏期和波幅，并使用SPSS 13.0软件进行统计分析。
P100波的潜伏期和波幅与检查尺寸呈曲线关系。在视力0.2组中，检查尺寸为10模拟时，P100潜伏期达到最小值，P100波幅显示峰值。其他组在检查尺寸为30'时显示最佳值。P100潜伏期和波幅与视力呈线性相关。随着视力的提高，P100波潜伏期缩短，波幅逐渐增大。还建立了视力与P100波潜伏期和波幅之间的回归模型。
基于PRVEP检查，利用较好的模拟角度，回归函数可为评估视力提供一种客观准确的方法。
