Terranova A
Plast Surg Nurs. 1991 Spring;11(1):20-5.
Diabetes mellitus delays wound healing. Hyperglycemia leads to osmotic diuresis and subsequent decreased oxygenation and perfusion. It also limits PMN functioning and produces malnutrition by increasing hormones that cause catabolism. With meticulous monitoring of blood glucose levels and intensive insulin therapy of the postsurgical patients with diabetes, hyperglycemia can be reduced. If hyperglycemia is contained at a level less than 200 mg/dl, attention can be focused on supportive measures to promote wound healing.
糖尿病会延迟伤口愈合。高血糖会导致渗透性利尿,进而导致氧合和灌注减少。它还会限制中性粒细胞的功能,并通过增加导致分解代谢的激素而造成营养不良。通过对糖尿病术后患者的血糖水平进行细致监测并进行强化胰岛素治疗,可以降低高血糖水平。如果将高血糖控制在低于200mg/dl的水平,就可以将注意力集中在促进伤口愈合的支持性措施上。