避免致命吸引力：生理条件下核小体和组蛋白伴侣的特性。
Avoiding a fatal attraction: properties of nucleosomes and a histone chaperone revealed under physiological conditions.
机构信息
Department of Biochemistry, University of Utah School of Medicine, 15 North Medical Drive East, Salt Lake City, UT 84112, USA.
出版信息
Mol Cell. 2010 Mar 26;37(6):747-8. doi: 10.1016/j.molcel.2010.02.016.
PMID:20347417
Abstract
Andrews et al. report a comprehensive thermodynamic analysis of nucleosomes in low salt, providing new insights into chromatin assembly and revealing an unexpected mechanism used by the histone chaperone Nap1 to prevent aberrant chromatin formation in vitro and in vivo.
摘要
安德鲁斯等人报告了低盐条件下核小体的综合热力学分析，为染色质组装提供了新的见解，并揭示了组蛋白伴侣 Nap1 在体外和体内防止异常染色质形成的一种意想不到的机制。
Zotero 插件