强效和选择性人碳酸酐酶VII（hCA VII）抑制剂的鉴定。 - Suppr

Suppr

超能文献

Identification of potent and selective human carbonic anhydrase VII (hCA VII) inhibitors.

作者信息

Gitto Rosaria, Agnello Stefano, Ferro Stefania, Vullo Daniela, Supuran Claudiu T, Chimirri Alba

机构信息

Dipartimento Farmaco-Chimico, Facoltà di Farmacia, Università di Messina, Viale Annunziata, 98168 Messina, Italy.

出版信息

ChemMedChem. 2010 Jun 7;5(6):823-6. doi: 10.1002/cmdc.201000044.

DOI:10.1002/cmdc.201000044

PMID:20349499

Abstract

摘要

相似文献

Identification of potent and selective human carbonic anhydrase VII (hCA VII) inhibitors.

ChemMedChem. 2010 Jun 7;5(6):823-6. doi: 10.1002/cmdc.201000044.

Carbonic anhydrase inhibitors. Phenacetyl-, pyridylacetyl- and thienylacetyl-substituted aromatic sulfonamides act as potent and selective isoform VII inhibitors.

Bioorg Med Chem Lett. 2009 Jun 15;19(12):3170-3. doi: 10.1016/j.bmcl.2009.04.123. Epub 2009 May 3.

4-[N-(substituted 4-pyrimidinyl)amino]benzenesulfonamides as inhibitors of carbonic anhydrase isozymes I, II, VII, and XIII.

Bioorg Med Chem. 2010 Nov 1;18(21):7413-21. doi: 10.1016/j.bmc.2010.09.011. Epub 2010 Sep 8.

Synthesis of novel acridine and bis acridine sulfonamides with effective inhibitory activity against the cytosolic carbonic anhydrase isoforms II and VII.

Bioorg Med Chem. 2013 Sep 15;21(18):5799-805. doi: 10.1016/j.bmc.2013.07.014. Epub 2013 Jul 17.

Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides.

Bioorg Med Chem Lett. 2005 Feb 15;15(4):971-6. doi: 10.1016/j.bmcl.2004.12.052.

Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inhibitors of human mitochondrial isoforms VA and VB.

Bioorg Med Chem. 2009 Jul 15;17(14):4894-9. doi: 10.1016/j.bmc.2009.06.006. Epub 2009 Jun 9.

Carbonic anhydrase inhibitors: synthesis and inhibition studies against mammalian isoforms I-XV with a series of 2-(hydrazinocarbonyl)-3-substituted-phenyl-1H-indole-5-sulfonamides.

Bioorg Med Chem. 2008 Oct 15;16(20):9113-20. doi: 10.1016/j.bmc.2008.09.032. Epub 2008 Sep 13.

Three new aromatic sulfonamide inhibitors of carbonic anhydrases I, II, IV and XII.

J Enzyme Inhib Med Chem. 2013 Apr;28(2):289-93. doi: 10.3109/14756366.2011.649269. Epub 2012 Feb 3.

Indapamide-like benzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, and XIII.

Bioorg Med Chem. 2010 Nov 1;18(21):7357-64. doi: 10.1016/j.bmc.2010.09.016. Epub 2010 Sep 15.

Anticonvulsant 4-aminobenzenesulfonamide derivatives with branched-alkylamide moieties: X-ray crystallography and inhibition studies of human carbonic anhydrase isoforms I, II, VII, and XIV.

J Med Chem. 2011 Jun 9;54(11):3977-81. doi: 10.1021/jm200209n. Epub 2011 May 9.

引用本文的文献

Benzenesulfonamides Incorporating Hydantoin Moieties Effectively Inhibit Eukaryoticand Human Carbonic Anhydrases.

Int J Mol Sci. 2022 Nov 15;23(22):14115. doi: 10.3390/ijms232214115.

In Silico-Guided Identification of New Potent Inhibitors of Carbonic Anhydrases Expressed in .

ACS Med Chem Lett. 2020 Sep 1;11(11):2294-2299. doi: 10.1021/acsmedchemlett.0c00417. eCollection 2020 Nov 12.

Looking toward the Rim of the Active Site Cavity of Druggable Human Carbonic Anhydrase Isoforms.

ACS Med Chem Lett. 2020 Mar 4;11(5):1000-1005. doi: 10.1021/acsmedchemlett.0c00062. eCollection 2020 May 14.

Screening of benzenesulfonamide in combination with chemically diverse fragments against carbonic anhydrase by differential scanning fluorimetry.

J Enzyme Inhib Med Chem. 2020 Dec;35(1):306-310. doi: 10.1080/14756366.2019.1698562.

Seeking new approach for therapeutic treatment of cholera disease via inhibition of bacterial carbonic anhydrases: experimental and theoretical studies for sixteen benzenesulfonamide derivatives.

J Enzyme Inhib Med Chem. 2019 Dec;34(1):1186-1192. doi: 10.1080/14756366.2019.1618292.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验