Department of Pathology, Vanderbilt University Medical Center, and Molecular Infectious Disease Laboratory, Vanderbilt University Hospital, 4605 TVC, Nashville, TN 37232-5310, USA.
J Clin Microbiol. 2010 May;48(5):1974-7. doi: 10.1128/JCM.00224-10. Epub 2010 Mar 29.
We report the identification and characterization of three Staphylococcus aureus isolates recovered from throat and vaginal cultures, as well as from an axillary abscess, of a 17-year-old female who died of tampon-related toxic shock syndrome. The three S. aureus isolates were unrelated as determined by pulsed-field gel electrophoresis. The vaginal isolate was mecA, Panton-Valentine leukocidin, and staphylococcal enterotoxin B and C negative, toxic shock syndrome toxin 1 positive, and staphylococcal cassette chromosome mec element (SCCmec) untypeable, which was consistent with the clinical and autopsy findings that death was due to tampon-related toxic shock syndrome.
我们报告了三株金黄色葡萄球菌分离株的鉴定和特征,这些分离株分别从一名 17 岁女性的咽喉和阴道培养物以及腋窝脓肿中分离得到,该女性因与卫生棉条相关的中毒性休克综合征而死亡。这三株金黄色葡萄球菌分离株通过脉冲场凝胶电泳确定为无关。阴道分离株 mecA、Panton-Valentine 白细胞毒素、金黄色葡萄球菌肠毒素 B 和 C 阴性,产毒性休克综合征毒素 1 阳性,且葡萄球菌盒式染色体 mec 元素(SCCmec)无法分型,这与临床和尸检结果一致,即死亡是由与卫生棉条相关的中毒性休克综合征引起的。