Sunil Kumar K, Lakshmi A Y, Srinivasa Rao P V L N, Das G C, Siva Kumar V
Department of Nephrology, Sri Venkateswara Institute of Medical Sciences, Tirupati, India.
Indian J Nephrol. 2009 Jan;19(1):13-4. doi: 10.4103/0971-4065.50674.
Accelerated atherosclerosis and cardiovascular disease are major causes of morbidity and mortality in patients of end-stage renal disease. Carotid intima media thickness is taken as a useful surrogate marker of atherosclerosis. Thirty end-stage renal disease (ESRD) patients were subjected to ultrasonography to study CIMT before the initiation of dialysis. CIMT was found to be higher in ESRD patients than in controls. Levels of a serum marker of oxidative stress were also found to be higher in patients than in the controls. CIMT is an easy, noninvasive, reproducible, and cost-effective investigation in patients with chronic renal failure.
加速性动脉粥样硬化和心血管疾病是终末期肾病患者发病和死亡的主要原因。颈动脉内膜中层厚度被视为动脉粥样硬化的一个有用替代标志物。对30例终末期肾病（ESRD）患者在开始透析前进行超声检查以研究颈动脉内膜中层厚度（CIMT）。发现ESRD患者的CIMT高于对照组。还发现患者血清氧化应激标志物水平高于对照组。对于慢性肾衰竭患者，CIMT是一种简便、无创、可重复且经济有效的检查方法。
