Deng J F, Jan I S, Cheng H S
National Poison Center, Veterans General Hospital, Taipei, Taiwan.
Vet Hum Toxicol. 1991 Apr;33(2):173-5.
Acute barium salt poisoning may cause acute hypokalemia and result in respiratory paralysis and ventricular tachyarrhythmias. The early nonspecific gastrointestinal symptoms of barium poisoning due to food contamination could be confused with other benign food poisonings. Early diagnosis and initiation of intensive supportive care is essential. We report an outbreak of acute barium carbonate poisoning, occurring at a family reunion party, which resulted in 9 hospital admissions. All of the victims initially developed nausea, vomiting, abdominal colic, dizziness and watery diarrhea followed by numbness of the face and distal extremities 1-2 h after ingesting fried flour-coated sweet potatoes. The flour was later confirmed to be contaminated with barium carbonate. One person died in the emergency room with a serum potassium level of 0.8 mEq/L. Two other victims developed ventricular tachycardia and respiratory paralysis but completely recovered with the treatment advice provided by the poison center. The poison center was successful in helping to make the correct diagnosis in a timely manner, immediately distribute the treatment protocol, and coordinate the laboratory confirmation of barium carbonate poisoning.
急性钡盐中毒可导致急性低钾血症,进而引发呼吸麻痹和室性快速心律失常。因食物污染导致的钡中毒早期非特异性胃肠道症状可能会与其他良性食物中毒相混淆。早期诊断并启动强化支持治疗至关重要。我们报告了一起在家庭聚会上发生的急性碳酸钡中毒事件,导致9人入院治疗。所有受害者最初出现恶心、呕吐、腹部绞痛、头晕和水样腹泻,在食用裹有面粉的油炸红薯1 - 2小时后,继而出现面部和四肢远端麻木。后来证实面粉被碳酸钡污染。1人在急诊室死亡,血清钾水平为0.8 mEq/L。另外2名受害者出现室性心动过速和呼吸麻痹,但按照中毒控制中心提供的治疗建议完全康复。中毒控制中心成功地及时协助做出了正确诊断,立即分发了治疗方案,并协调了碳酸钡中毒的实验室确认工作。