Department of Diagnostic Radiology, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, [corrected] Taiwan.
Am J Transplant. 2010 May;10(5):1276-83. doi: 10.1111/j.1600-6143.2010.03076.x. Epub 2010 Mar 26.
To evaluate the efficacy of stent placement in the treatment of portal vein (PV) stenosis or occlusion in living donor liver transplant (LDLT) recipients, 468 LDLT records were reviewed. Sixteen (10 PV occlusions and 6 stenoses) recipients (age range, 8 months-59 years) were referred for possible interventional angioplasty (dilatation and/or stent) procedures. Stent placement was attempted in all. The approaches used were percutaneous transhepatic (n = 10), percutaneous transsplenic (n = 4), and intraoperative (n = 2). Technical success was achieved in 11 of 16 patients (68.8%). The sizes of the stents used varied from 7 mm to 10 mm in diameter. In the five unsuccessful patients, long-term complete occlusion of the PV with cavernous transformation precluded catherterization. The mean follow-up was 12 months (range, 3-24). The PV stent patency rate was 90.9% (10/11). Rethrombosis and occlusion of the stent and PV occurred in a single recipient who had a cryoperserved vascular graft to reconstruct the PV during the LDLT operation. PV occlusion of >1 year with cavernous transformation seemed to be a factor causing technical failure. In conclusion, early treatment of PV stenosis and occlusion by stenting is an effective treatment in LDLT. Percutaneous transhepatic and transsplenic, and intraoperative techniques are effective approaches depending on the situation.
为了评估支架置入术治疗活体肝移植(LDLT)受者门静脉(PV)狭窄或闭塞的疗效,我们回顾了 468 份 LDLT 记录。16 名(10 例 PV 闭塞和 6 例狭窄)受者(年龄 8 个月至 59 岁)因可能需要介入血管成形术(扩张和/或支架)而转介。所有患者均尝试进行支架置入术。采用的方法包括经皮经肝(n = 10)、经皮经脾(n = 4)和术中(n = 2)。16 例患者中有 11 例(68.8%)获得技术成功。使用的支架直径从 7 毫米到 10 毫米不等。在 5 例未成功的患者中,PV 的长期完全闭塞伴海绵样变使得无法进行导管插入术。平均随访时间为 12 个月(范围 3-24 个月)。11 例患者中有 10 例(90.9%)PV 支架通畅。1 例接受 cryoperserved 血管移植物重建 PV 的 LDLT 手术的患者发生了支架和 PV 再血栓形成和闭塞。>1 年的 PV 闭塞伴海绵样变似乎是导致技术失败的因素。总之,支架置入术早期治疗 LDLT 后的 PV 狭窄和闭塞是一种有效的治疗方法。经皮经肝和经皮经脾,以及术中技术是有效的方法,具体取决于情况。