Uchida Y, Oshima T, Fujimori Y, Hirose J, Mukai H, Kawashima M
Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.
Am Heart J. 1991 Jun;121(6 Pt 1):1791-8. doi: 10.1016/0002-8703(91)90028-g.
The feasibility of percutaneous translumial angioscopy of the cardiac valves was examined in eight patients with and in 11 patients without valvular disease. In eight of these patients, a guiding balloon catheter (9F) was introduced into the aortic root, a guide wire (0.014 or 0.025 inch) was introduced through the catheter into the left ventricle to prevent dislocation of the catheter, and a fiberscope (1.6 or 4.6F) was advanced to the distal tip of the catheter. The balloon was then inflated with carbon dioxide and was manipulated against the aortic valve; a body temperature heparinized saline was infused through the catheter for observation. Similarly, the balloon catheter was advanced transseptally into the left atrium for observation of the mitral valve in four patients. Also, the balloon catheter was advanced through the right femoral vein into the right atrium for observation of the tricupid valve in three patients. In patients with a normal aortic valve, the aortic cusp surface was smooth and white and the edges were sharp. They opened briskly during systole and coapted each other completely during diastole. In rheumatic aortic regurgitation, the cuspus were thick and blunt and their coaptation insufficiency was observed during diastole. In a patient with rheumatic AS, globular and yellow cusps were observed. Mitral valve leaflets were smooth and white in a patients without mitral valvular disease, while the leaflets were yellow, thick and irregular, and blood regurgitation from the left ventricle into the left atrium could be observed in two patients with rheumatic MSR. The process of opening and closure of a tricuspid valve was also observed in three patients without tricuspid valvular disease.(ABSTRACT TRUNCATED AT 250 WORDS)
在8例有心脏瓣膜病和11例无瓣膜病的患者中检查了经皮腔内心脏瓣膜血管镜检查的可行性。在其中8例患者中,将引导球囊导管(9F)插入主动脉根部,通过该导管将导丝(0.014或0.025英寸)插入左心室以防止导管移位,然后将纤维镜(1.6或4.6F)推进到导管的远端。然后用二氧化碳使球囊膨胀,并使其抵住主动脉瓣;通过导管注入体温的肝素化盐水进行观察。同样,将球囊导管经房间隔推进到左心房,对4例患者的二尖瓣进行观察。此外,将球囊导管经右股静脉推进到右心房,对3例患者的三尖瓣进行观察。在主动脉瓣正常的患者中,主动脉瓣叶表面光滑、呈白色,边缘锐利。它们在收缩期迅速打开,在舒张期完全相互贴合。在风湿性主动脉瓣反流患者中,瓣叶增厚、钝圆,在舒张期观察到它们的贴合不全。在一名风湿性主动脉瓣狭窄患者中,观察到球状且发黄的瓣叶。在无二尖瓣疾病的患者中,二尖瓣叶光滑、呈白色,而在两名风湿性二尖瓣反流患者中,瓣叶发黄、增厚且不规则,可观察到血液从左心室反流至左心房。还对3例无三尖瓣疾病的患者观察了三尖瓣的开闭过程。(摘要截断于250字)