Uchida Y, Tomaru T, Nakamura F, Sonoki H, Sugimoto T
Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.
Am Heart J. 1988 Jun;115(6):1297-302. doi: 10.1016/0002-8703(88)90024-5.
The applicability of fiberoptic angioscopy with a guiding balloon catheter to observe the cardiac chambers, valves and the great vessels was examined in anesthetized dogs. A No. 11 French guiding balloon catheter (balloon diameter 50 French) was introduced through either the right jugular vein or the right femoral vein into the right heart, and then a fiberscope (4.3 French in diameter) was introduced through the catheter into the right heart in 10 dogs. The balloon was inflated with air and gently pushed against the luminal surface, warm saline was infused through the catheter to displace the blood, and the luminal surfaces were photographed on 16 mm color cinefilms. Pulmonary angioscopy was also performed in these dogs. Similarly, the guiding catheter and fiberscope were introduced through the right common carotid artery into the left ventricle for observation of the luminal changes in the other 10 dogs. The luminal surfaces of the superior vena cava, right atrium, right ventricle, and pulmonary artery could be observed in all dogs. The trabeculae of the left ventricle, contracting and relaxing synchronously with the cardiac beat, could also be observed in all dogs. However, observations of the tricuspid valve, aortic valve, papillary muscle, and chordae were successful in only some dogs. Postmortem examinations revealed no obvious endocardial or intimal damage. The results indicate the applicability and safety of angioscopy guided by a balloon catheter for observations of the luminal changes in the cardiac chambers and great vessels.
在麻醉犬身上检查了带有引导球囊导管的纤维血管镜观察心腔、瓣膜和大血管的适用性。将一根11号法国引导球囊导管（球囊直径50法国）经右颈静脉或右股静脉插入右心，然后在10只犬中经该导管将一根纤维镜（直径4.3法国）插入右心。向球囊内充气并轻轻压向管腔表面，经导管注入温盐水以驱血，然后在16毫米彩色电影胶片上拍摄管腔表面。这些犬还进行了肺动脉血管镜检查。同样，在另外10只犬中，将引导导管和纤维镜经右颈总动脉插入左心室以观察管腔变化。所有犬均能观察到上腔静脉、右心房、右心室和肺动脉的管腔表面。所有犬也能观察到与心跳同步收缩和舒张的左心室小梁。然而，仅在部分犬中成功观察到了三尖瓣、主动脉瓣、乳头肌和腱索。尸检未发现明显的心内膜或内膜损伤。结果表明，球囊导管引导的血管镜检查对于观察心腔和大血管的管腔变化具有适用性和安全性。
