Bioanalysis Research Group, IMIM-Hospital del Mar, Dr Aiguader 88, Barcelona, Spain.
Drug Test Anal. 2009 Nov;1(11-12):479-84. doi: 10.1002/dta.55.
There are many areas of common interest between anti-doping laboratories and those working in the clinical, legal and forensic fields. In addition to methodological similarities, there are aspects of the findings in sport drug testing that overlap with other fields in such a way that sport drug testing and clinical, legal or forensic work may benefit from mutual interaction. Three recent examples are presented from the author's experience. Case report 1 concerns the clinical relevance of hCG findings in sport drug testing as potential indicators of the presence of a (testicular) tumour in athletes. Case report 2 refers to difficulties that accredited laboratories can encounter due to differences between national legal systems and the administrative regulation systems of sport authorities. The example involves a network of blood collection for further autologous transfusion. Case report 3 relates to additional forensic-type investigations needed to interpret a situation where intoxication of a whole delegation was responsible for apparent doping cases. Clinical, legal and forensic fields must recognize the added value that some results and developments coming from anti-doping laboratories may have. At the same time anti-doping analysts should be aware of new issues, methodologies and problems appearing in related fields.
兴奋剂检测实验室与从事临床、法律和法医学领域工作的实验室有许多共同关注的领域。除了方法学上的相似之处，运动药物检测中的某些发现与其他领域存在重叠，以至于运动药物检测以及临床、法律或法医工作可能受益于相互作用。作者从自身经验中提出了三个最近的例子。案例报告 1 涉及运动药物检测中 hCG 检测结果的临床相关性，因为它们可能是运动员存在（睾丸）肿瘤的潜在指标。案例报告 2 提到了由于国家法律制度和体育主管部门的行政监管制度之间的差异，认可实验室可能遇到的困难。该例子涉及一个用于进一步自体输血的血液采集网络。案例报告 3 涉及到解释一个整个代表团中毒导致明显兴奋剂案例的情况所需的额外法医类型调查。临床、法律和法医领域必须认识到来自兴奋剂检测实验室的某些结果和发展可能具有的附加值。同时，反兴奋剂分析人员应该意识到相关领域出现的新问题、新方法和新问题。
