Laboratoire National de Santé-Toxicologie, Université du Luxembourg, Luxembourg.
Drug Test Anal. 2009 Apr;1(4):153-5. doi: 10.1002/dta.32.
In 1850 the Belgian Count Hypolyte Visart de Bocarmé was accused of having killed his brother-in-law Gustave Fougnies by poisoning with nicotine. Bocarmé had isolated nicotine from tobacco leaves (Nicotiana tabacum). J. S. Stas (1813-1891) was committed expert and managed to convince the poisoner. He was the first scientist to deproteinize organ tissues by alcohol and could successfully identify nicotine after diethyl ether extraction from the victim's organs. During court trial this identification was challenged by his mentor M. J. B. Orfila from Paris, who had stated 3 years before, that it would never be possible to isolate and identify organic poisons from organ tissues.
1850 年，比利时伯爵 Hypolyte Visart de Bocarmé 被指控用尼古丁毒杀其姐夫 Gustave Fougnies。Bocarmé 从烟草叶（Nicotiana tabacum）中分离出尼古丁。J. S. Stas（1813-1891）是受委托的专家，并成功说服了毒杀者。他是第一个通过酒精使组织器官去蛋白化的科学家，并能够成功地从受害者器官的乙醚提取物中鉴定出尼古丁。在法庭审判中，他的导师来自巴黎的 M. J. B. Orfila 对这一鉴定提出质疑，他在 3 年前曾表示，从器官组织中分离和鉴定有机毒物是不可能的。
