Discipline of Surgery, School of Medicine, James Cook University, Clinical School 1MB52, Angus Smith Dr, Douglas, Townsville, QLD 4811, Australia.
World J Gastroenterol. 2010 Apr 7;16(13):1610-21. doi: 10.3748/wjg.v16.i13.1610.
Colorectal anastomotic leak remains one of the most feared post-operative complications, particularly after anterior resection of the rectum with, the shift from abdomino-peritoneal resections to total mesorectal excision and primary anastomosis. The literature fails to demonstrate superiority of stapled over hand-sewn techniques in colorectal anastomosis, regardless of the level of anastomosis, although a high stricture rate was noted in the former technique. Thus, improvements in safety aspects of anastomosis and alternatives to hand-sewn and stapled techniques are being sought. Here, we review alternative anastomotic techniques used to fashion bowel anastomosis. Compression anastomosis using compression anastomotic clips, endoluminal compression anastomotic rings, AKA-2, biofragmental anastomotic rings, or Magnamosis all involve the concept of creating a sutureless end-to-end anastomosis by compressing two bowel ends together, leading to a simultaneous necrosis and healing process that joins the two lumens. Staple line reinforcement is a new approach that reduce the drawbacks of staplers used in colorectal practice, i.e. leakage, bleeding, misfiring, and inadequate tissue approximation. Various non-absorbable, semi or fully absorbable materials are now available. Two other techniques can provide alternative anastomotic support to the suture line: a colorectal drain and a polyester stent, which can be utilized in ultra-low rectal excision and can negate the formation of a defunctioning stoma. Doxycycline coated sutures have been used to overcome the post-operative weakness in anastomosis secondary to rapid matrix degradation mediated by matrix metalloproteinase. Another novel technique, the electric welding system, showed promising results in construction of a safe, neat, smooth sutureless bowel anastomosis. Various anastomotic techniques have been shown to be comparable to the standard techniques of suturing and stapling. However, most of these alternatives need to be accepted and optimized for future use.
结直肠吻合口漏仍然是最可怕的术后并发症之一,尤其是在直肠前切除术后,从腹会阴联合切除术转变为全直肠系膜切除术和一期吻合。文献表明,无论吻合部位如何,吻合钉技术并不优于手工缝合技术,但前者的吻合口狭窄发生率较高。因此,人们正在寻求提高吻合安全性的方法,并寻求替代手工缝合和吻合钉技术的方法。在这里,我们回顾了用于制作肠吻合的替代吻合技术。使用压缩吻合夹、腔内压缩吻合环、AKA-2、生物可降解吻合环或 Magnamosis 的压缩吻合,都涉及通过将两个肠端压缩在一起创建无缝合端端吻合的概念,导致两个管腔同时坏死和愈合过程。吻合钉线加固是一种新的方法,可以减少结直肠手术中吻合钉的缺点,即渗漏、出血、卡壳和组织贴合不充分。现在有各种不可吸收、半吸收或全吸收材料可供选择。另外两种技术可以为吻合线提供替代的吻合支持:结肠直肠引流管和聚酯支架,可用于超低直肠切除,并可避免形成功能性造口。多西环素涂层缝线已被用于克服由基质金属蛋白酶介导的快速基质降解引起的术后吻合口虚弱。另一种新的技术,即电焊接系统,在构建安全、整齐、光滑的无缝合肠吻合方面显示出有前途的结果。各种吻合技术已被证明与缝合和吻合钉的标准技术相当。然而,这些替代方法中的大多数需要被接受和优化,以便将来使用。