Department of Medicine, Advocate Christ Medical Center/University of Illinois at Chicago, 4440 West 95th Street, Oak Lawn, IL 60453, USA.
Heart Lung Circ. 2010 Jul;19(7):435-7. doi: 10.1016/j.hlc.2010.01.008. Epub 2010 Mar 30.
Amiodarone pulmonary toxicity (APT) is a common and distinctive form of drug-induced lung injury. Several patterns have been described and the most common pattern of APT is interstitial pneumonitis. However, amiodarone-induced diffused alveolar haemorrhage is rarely reported. We describe a case of early onset of APT manifested by respiratory distress, haemoptysis, severe hypoxia and bilateral pulmonary infiltrates that was finally diagnosed with amiodarone-induced diffuse alveolar haemorrhage. High suspicion of APT in patients with these non-specific clinical symptoms is needed. Early recognition and treatment are imperative.
胺碘酮肺毒性（APT）是一种常见且具有特征性的药物诱导性肺损伤。已经描述了几种模式，最常见的 APT 模式是间质性肺炎。然而，胺碘酮诱导的弥漫性肺泡出血很少报道。我们描述了一例早期 APT 的病例，表现为呼吸窘迫、咯血、严重缺氧和双侧肺部浸润，最终诊断为胺碘酮诱导的弥漫性肺泡出血。对于这些非特异性临床症状的患者，需要高度怀疑 APT。早期识别和治疗至关重要。
