Department of Internal Medicine, Kangwon National University Hospital, Chuncheon, Korea.
Korean Circ J. 2013 Oct;43(10):699-701. doi: 10.4070/kcj.2013.43.10.699. Epub 2013 Oct 30.
Amiodarone is a widely used antiarrhythmic agent. Among its various adverse effects, amiodarone-induced pulmonary toxicity (APT) is the most life threatening complication, which has been described mostly in patients who have been in treatment with high accumulative doses for a long duration of time. However, amiodarone therapy in short-term duration induced APT was rarely reported. We describe a case of a 54-year-old man who is presented with symptoms of APT after a few days of therapy for post-myocardial infarction ventricular tachycardia. For early diagnosis and successful treatment, awareness and high suspicion of this rare type of early onset APT is crucial in patients with amiodarone therapy.
胺碘酮是一种广泛应用的抗心律失常药物。在其各种不良反应中，胺碘酮引起的肺毒性（APT）是最具威胁生命的并发症，这种情况大多发生在长期接受高累积剂量治疗的患者中。然而，短期胺碘酮治疗引起的 APT 很少有报道。我们描述了一例 54 岁男性患者，在心肌梗死后室性心动过速治疗几天后出现 APT 症状。为了早期诊断和成功治疗，对于接受胺碘酮治疗的患者，早期发病的这种罕见类型 APT 的早期诊断和高度怀疑至关重要。
