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肝脏巨大血管瘤:观察还是切除?

Giant haemangioma of the liver: observation or resection?

机构信息

Clinical and Surgical Sciences (Surgery), University of Edinburgh, Royal Infirmary, Edinburgh, UK.

出版信息

Dig Surg. 2010;27(1):7-11. doi: 10.1159/000268108. Epub 2010 Apr 1.

Abstract

BACKGROUND

Haemangiomata are the most frequent benign solid liver lesion. The management of giant (> or =5 cm) haemangiomata of the liver remains controversial.

METHODS

A search of relevant peer-reviewed literature was conducted using PubMed and original articles were reviewed.

RESULTS AND CONCLUSIONS

The vast majority of giant haemangiomata remain asymptomatic and have a benign and uncomplicated natural history. Decisions regarding the optimal management of giant haemangiomata depend on a high level of confidence in diagnostic imaging. Diagnostic biopsy to differentiate giant haemangiomata from malignant lesions should be discouraged. Despite limitations and alternative modalities, surgery remains the only consistently effective curative treatment for giant haemangiomata. Surgery is not generally justified to prevent complications in asymptomatic patients. Principal indications for the surgical management of giant haemangiomata include established complications, incapacitating symptoms and uncertainty of diagnosis. Patients should only be selected for surgery based on a careful assessment of risks and benefits of intervention.

摘要

背景

血管瘤是最常见的肝脏良性实体瘤。肝脏巨大(≥5cm)血管瘤的处理仍存在争议。

方法

使用 PubMed 对相关的同行评审文献进行了检索,并对原始文章进行了回顾。

结果与结论

绝大多数巨大血管瘤无症状,具有良性和简单的自然病史。决定巨大血管瘤的最佳治疗方案取决于对诊断影像学的高度信心。为了区分巨大血管瘤和恶性病变而进行的诊断性活检应予以避免。尽管存在局限性和替代方式,手术仍然是治疗巨大血管瘤唯一始终有效的方法。对于无症状患者,手术通常不能用于预防并发症。手术治疗巨大血管瘤的主要适应证包括已确定的并发症、引起不适的症状和诊断不确定。只有在仔细评估干预的风险和益处后,才能选择患者进行手术。

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