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西部菱斑响尾蛇毒液的降压活性:其来源的鉴定。

The hypotensive activity of Crotalus atrox (western diamondback rattlesnake) venom: identification of its origin.

作者信息

de Mesquita L C, Selistre H S, Giglio J R

机构信息

Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Brazil.

出版信息

Am J Trop Med Hyg. 1991 Mar;44(3):345-53. doi: 10.4269/ajtmh.1991.44.345.

DOI:10.4269/ajtmh.1991.44.345
PMID:2035756
Abstract

Viperidae snakes belonging to the genus Crotalus, subfamily Crotalinae, include the species durissus terrificus, durissus durissus, adamanteus, atrox, cerastes, horridus, molossus, scutulatus, viridis and others. All of them, except for the first 2, are found in North America. Crotalus atrox, or diamondback rattlesnakes, live in the southwest United States and in Mexico. This paper describes the fractionation of C. atrox venom in order to isolate and identify its hypotensive agents.

摘要

蝰蛇科响尾蛇属(Crotalus)、蝮亚科(Crotalinae)的蛇类包括杜氏侏膨蝰(Crotalus durissus terrificus)、杜氏膨蝰(Crotalus durissus durissus)、东部菱斑响尾蛇(Crotalus adamanteus)、西部菱斑响尾蛇(Crotalus atrox)、角响尾蛇(Crotalus cerastes)、多斑响尾蛇(Crotalus horridus)、墨西哥响尾蛇(Crotalus molossus)、莫哈维响尾蛇(Crotalus scutulatus)、草原响尾蛇(Crotalus viridis)等物种。除前两种外,其他所有物种均分布于北美洲。西部菱斑响尾蛇(Crotalus atrox),即菱斑响尾蛇,生活在美国西南部和墨西哥。本文描述了西部菱斑响尾蛇毒液的分级分离,以便分离和鉴定其降压成分。

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