Discipline of Medical Radiations, School of Medical Sciences, Bundoora West Campus, Royal Melbourne Institute of Technology University, Bundoora, Victoria 3083, Australia.
Singapore Med J. 2010 Feb;51(2):e37-9.
The aim of this report was to assess the changes in the 18F-fluorodeoxyglucose (18F-FDG) uptake of brown fats on integrated positron emission tomography/computed tomography (PET/CT) imaging. The patient presented with an enlargement of the neck lymph nodes, and was suspicious for tuberculous lymphadenitis. A whole body PET/CT imaging was performed, followed by a delayed imaging of the neck and thoracic regions. A visually increased 18F-FDG uptake was taken as a positive finding. A semi-quantitative evaluation was performed using a maximum standardised uptake value (SUVmax), with a cut-off value above 2.5. There were a number of 18F-FDG avid activity areas seen at the supraclavicular, mediastinal, paravertebral and perirenal regions. These are in keeping with the physiological 18F-FDG uptake in brown fat. The differences in SUVmax between the two images ranged from -20 percent to +20 percent. Based on our observations, dual time point imaging may not be a reliable method for assessing the 18F-FDG uptake of brown fat.
本报告旨在评估整合正电子发射断层扫描/计算机断层扫描（PET/CT）成像中棕色脂肪 18F-氟脱氧葡萄糖（18F-FDG）摄取的变化。该患者因颈部淋巴结肿大就诊，疑似结核性淋巴结炎。进行全身 PET/CT 成像，然后对颈部和胸部区域进行延迟成像。视觉上增加的 18F-FDG 摄取被视为阳性发现。使用最大标准化摄取值（SUVmax）进行半定量评估，截断值高于 2.5。在锁骨上、纵隔、椎旁和肾周区域可见多个 18F-FDG 高活性区域。这些与棕色脂肪的生理性 18F-FDG 摄取一致。两张图像之间的 SUVmax 差异在-20%至+20%之间。根据我们的观察，双时相成像可能不是评估棕色脂肪 18F-FDG 摄取的可靠方法。
