Growth, Exercise, Nutrition and Development (GENUD) Research group, University of Zaragoza, Spain.
J Physiol Biochem. 2009 Dec;65(4):415-20. doi: 10.1007/BF03185937.
The aim of this study was to investigate fat distribution, mainly abdominal fat, and its relationship with metabolic risk variables in a group of 126 children and adolescents (60 males and 66 females) aged 5.0 to 14.9. According to IOTF criteria, 46 were classified as normal weight, 28 overweight and 52 obese. Weight, height, waist (WC) and hip circumferences were measured. The body mass index (BMI) was calculated. Total body fat, trunkal and abdominal fat were also assessed by dual energy x-ray absorptiometry (DXA). Glucose, insulin, HDL-Cholesterol, triglycerides (TG), ferritine, homocystein and C-reactive protein (CRP) were measured. Obesity status was related with insulin concentrations, CRP, TG and HDL. Obese patients had higher abdominal fat and higher CRP values than overweight and normal subjects. All markers of central body adiposity were related with insulin and lipid metabolism; however, they were not related with homocystein or ferritin. A simple anthropometric measurement, like waist circumference, seems to be a good predictor of the majority of the obesity related metabolic risk variables.
本研究旨在调查 126 名 5.0 至 14.9 岁儿童和青少年（60 名男性和 66 名女性）的脂肪分布，主要是腹部脂肪，及其与代谢风险变量的关系。根据 IOTF 标准，46 人被归类为正常体重，28 人超重，52 人肥胖。测量体重、身高、腰围（WC）和臀围。计算体重指数（BMI）。还通过双能 X 射线吸收法（DXA）评估全身脂肪、躯干脂肪和腹部脂肪。测量血糖、胰岛素、HDL-胆固醇、甘油三酯（TG）、铁蛋白、同型半胱氨酸和 C 反应蛋白（CRP）。肥胖状况与胰岛素浓度、CRP、TG 和 HDL 有关。肥胖患者的腹部脂肪和 CRP 值高于超重和正常受试者。所有中心体脂的标志物都与胰岛素和脂质代谢有关；然而，它们与同型半胱氨酸或铁蛋白无关。腰围等简单的人体测量指标似乎是大多数肥胖相关代谢风险变量的良好预测指标。
