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年轻患者中固定和活动衬垫全膝关节置换术后的骨溶解。

Osteolysis in well-functioning fixed- and mobile-bearing TKAs in younger patients.

机构信息

The Joint Replacement Center of Korea, Ewha Womans University School of Medicine, 911-1, MokDong, YangChun-Gu, Seoul, 158-710, Korea.

出版信息

Clin Orthop Relat Res. 2010 Nov;468(11):3084-93. doi: 10.1007/s11999-010-1336-2. Epub 2010 Apr 1.

Abstract

BACKGROUND

Periprosthetic osteolysis is an increasingly prevalent complication of TKA. To reduce the polyethylene wear and periprosthetic osteolysis, particularly in young patients, the design of the contemporary fixed-bearing TKAs has been modified and mobile-bearing TKAs have been introduced.

QUESTIONS/PURPOSES: We asked whether the prevalence of osteolysis would be less in well-functioning mobile-bearing TKAs than in well-functioning contemporary fixed-bearing TKAs in young patients.

PATIENTS AND METHODS

We compared 488 patients (894 knees) who received fixed-bearing knee prostheses with 445 patients (816 knees) who received mobile-bearing knee prostheses. There were 187 men and 301 women (mean age, 58.6 years; range, 33-65 years) in the fixed-bearing group and 167 men and 278 women (mean age, 55.7 years; range, 33-65 years) in the mobile-bearing group. The mean followup was 12.6 years (range, 10-17 years) in the fixed-bearing group and 12.9 years (range, 10-17 years) in the mobile-bearing group.

RESULTS

The incidence of osteolysis was 1.6% (14 of 894 knees) in the fixed-bearing group and 2.2% (18 of 816 knees) in the mobile-bearing group at the final review. The mean postoperative Knee Society knee and function scores were 92.9 points and 83.5 points, respectively, in the fixed-bearing group and 90.7 points and 83.8 points, respectively, in the mobile-bearing group. The revision rates were 3.7% (33 of 894 knees) in the fixed-bearing group and 2.7% (22 of 816 knees) in the mobile-bearing group.

CONCLUSIONS

We found the incidence of osteolysis, rate of revision, and implant survivorship were similar between fixed-bearing and mobile-bearing TKAs in younger patients.

摘要

背景

假体周围骨溶解是 TKA 越来越普遍的并发症。为了减少聚乙烯磨损和假体周围骨溶解,特别是在年轻患者中,当代固定轴承 TKA 的设计已经修改,并引入了活动轴承 TKA。

问题/目的:我们想知道在年轻患者中,功能良好的活动轴承 TKA 的骨溶解发生率是否会低于功能良好的当代固定轴承 TKA。

患者和方法

我们比较了接受固定轴承膝关节假体的 488 例患者(894 膝)和接受活动轴承膝关节假体的 445 例患者(816 膝)。固定轴承组 187 例为男性,301 例为女性(平均年龄 58.6 岁;范围 33-65 岁);活动轴承组 167 例为男性,278 例为女性(平均年龄 55.7 岁;范围 33-65 岁)。固定轴承组的平均随访时间为 12.6 年(范围 10-17 年),活动轴承组为 12.9 年(范围 10-17 年)。

结果

在最终随访时,固定轴承组骨溶解发生率为 1.6%(894 膝中 14 膝),活动轴承组为 2.2%(816 膝中 18 膝)。固定轴承组术后膝关节协会膝关节评分和功能评分分别为 92.9 分和 83.5 分,活动轴承组分别为 90.7 分和 83.8 分。固定轴承组的翻修率为 3.7%(894 膝中 33 膝),活动轴承组为 2.7%(816 膝中 22 膝)。

结论

我们发现,在年轻患者中,固定轴承和活动轴承 TKA 的骨溶解发生率、翻修率和假体存活率相似。

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