Sesorova I S, Lazorenko T V
Morfologiia. 2009;136(6):57-61.
Using the standard cryodestruction model, the peculiarities of reparative regeneration were studied in cat thoracic duct endothelium. Material was collected 12 hours, 1, 2 and 3 days after the injury and was analyzed using scanning electron microscopy. The restoration of the endothelial layer was shown to be completed by day 3 due to cell migration and proliferation at the margin of cryodestruction zone. The degree of tissue regeneration was evaluated using the topological and informational parameters. The results demonstrated the imperfect completion of regeneration process by day 3; the borderline state of the cellular system was detected together with the possibility of the disturbance of endothelial lining reorganization process. Thus, the informational parameters may be used as the complementary criteria for the assessment of the processes, cellular system state and functioning.
利用标准冷冻破坏模型，研究了猫胸导管内皮修复性再生的特点。在损伤后12小时、1天、2天和3天收集材料，并使用扫描电子显微镜进行分析。结果表明，由于冷冻破坏区边缘的细胞迁移和增殖，内皮细胞层在第3天恢复完成。利用拓扑学和信息学参数评估组织再生程度。结果表明，到第3天再生过程未完全完成；检测到细胞系统的临界状态以及内皮衬里重组过程受到干扰的可能性。因此，信息学参数可作为评估这些过程、细胞系统状态和功能的补充标准。
