Research Unit, Centre for Military Medicine, P.O. Box 50, FIN-00301 Helsinki, Finland.
J Bone Joint Surg Am. 2010 Apr;92(4):927-34. doi: 10.2106/JBJS.H.01527.
This diagnostic study was performed to determine the correlation between anterior knee pain and chondromalacia patellae and to define the reliability of magnetic resonance imaging for the diagnosis of chondromalacia patellae.
Fifty-six young adults (median age, 19.5 years) with anterior knee pain had magnetic resonance imaging of the knee followed by arthroscopy. The patellar chondral lesions identified by magnetic resonance imaging were compared with the arthroscopic findings.
Arthroscopy confirmed the presence of chondromalacia patellae in twenty-five (45%) of the fifty-six knees, a synovial plica in twenty-five knees, a meniscal tear in four knees, and a femorotibial chondral lesion in four knees; normal anatomy was seen in six knees. No association was found between the severity of the chondromalacia patellae seen at arthroscopy and the clinical symptoms of anterior knee pain syndrome (p = 0.83). The positive predictive value for the ability of 1.0-T magnetic resonance imaging to detect chondromalacia patellae was 75% (95% confidence interval, 53% to 89%), the negative predictive value was 72% (95% confidence interval, 56% to 84%), the sensitivity was 60% (95% confidence interval, 41% to 77%), the specificity was 84% (95% confidence interval, 67% to 93%), and the diagnostic accuracy was 73% (95% confidence interval, 60% to 83%). The sensitivity was 13% (95% confidence interval, 2% to 49%) for grade-I lesions and 83% (95% confidence interval, 59% to 94%) for grade-II, III, or IV lesions.
Chondromalacia patellae cannot be diagnosed on the basis of symptoms or with current physical examination methods. The present study demonstrated no correlation between the severity of chondromalacia patellae and the clinical symptoms of anterior knee pain syndrome. Thus, symptoms of anterior knee pain syndrome should not be used as an indication for knee arthroscopy. The sensitivity of 1.0-T magnetic resonance imaging was low for grade-I lesions but considerably higher for more severe (grade-II, III, or IV) lesions. Magnetic resonance imaging may be considered an accurate diagnostic tool for identification of more severe cases of chondromalacia patellae.
本研究旨在确定膝关节前痛与髌骨软骨软化症之间的相关性,并确定磁共振成像在髌骨软骨软化症诊断中的可靠性。
对 56 例膝关节前痛的年轻患者进行膝关节磁共振成像检查,然后行关节镜检查。磁共振成像发现的髌软骨病变与关节镜检查结果进行比较。
关节镜检查证实 56 例膝关节中 25 例(45%)存在髌骨软骨软化症,25 例存在滑膜皱襞,4 例存在半月板撕裂,4 例存在股骨胫骨软骨病变;6 例膝关节正常。关节镜下髌骨软骨软化症的严重程度与膝关节前痛综合征的临床症状无相关性(p=0.83)。1.0-T 磁共振成像诊断髌骨软骨软化症的阳性预测值为 75%(95%置信区间,53%89%),阴性预测值为 72%(95%置信区间,56%84%),敏感度为 60%(95%置信区间,41%77%),特异度为 84%(95%置信区间,67%93%),诊断准确率为 73%(95%置信区间,60%83%)。Ⅰ级病变的敏感度为 13%(95%置信区间,2%49%),Ⅱ、Ⅲ或Ⅳ级病变的敏感度为 83%(95%置信区间,59%~94%)。
不能根据症状或现有的体格检查方法诊断髌骨软骨软化症。本研究表明,髌骨软骨软化症的严重程度与膝关节前痛综合征的临床症状之间无相关性。因此,膝关节前痛综合征的症状不应作为膝关节镜检查的指征。1.0-T 磁共振成像对Ⅰ级病变的敏感度较低,但对更严重(Ⅱ、Ⅲ或Ⅳ级)病变的敏感度较高。磁共振成像可作为髌骨软骨软化症更严重病例的准确诊断工具。