细胞竞争：纠结之岸的海盗。

Cell competition: pirates on the tangled bank.

机构信息

St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

出版信息

Cell Stem Cell. 2010 Apr 2;6(4):287-288. doi: 10.1016/j.stem.2010.03.006.

DOI:10.1016/j.stem.2010.03.006

PMID:20362527

Abstract

Competition by stem cells for occupation of a limited niche is a well-described phenomenon. Two recent studies highlight competition between hematopoietic stem cells based on p53. These findings have implications for both normal homeostasis and tumorigenesis.

摘要

干细胞竞争有限龛位的占据是一个描述得很好的现象。最近的两项研究强调了基于 p53 的造血干细胞之间的竞争。这些发现对正常的体内平衡和肿瘤发生都有影响。