麻醉诱导的杰韦尔和朗格-尼尔森综合征患者室性快速性心律失常

Anaesthetic-induced ventricular tachyarrhythmia in Jervell and Lange-Nielsen syndrome.

作者信息

Adu-Gyamfi Y, Said A, Chowdhary U M, Abomelha A, Sanyal S K

机构信息

Department of Anaesthesiology, King Faisal University, College of Medicine, Dammam, Saudi Arabia.

出版信息

Can J Anaesth. 1991 Apr;38(3):345-6. doi: 10.1007/BF03007627.

DOI:10.1007/BF03007627

PMID:2036697

Abstract

A four-year-old deaf girl with a history of convulsions developed polymorphous ventricular tachycardia during induction of anaesthesia. The arrhythmia reverted to sinus rhythm spontaneously. Post-anaesthetic ECG showed marked prolongation of the QTc interval (570-690 msec). Deafness and prolonged QTc interval in association with microcytic-hypochromic anaemia confirmed the diagnosis of the Jervell and Lange-Nielsen syndrome. This case report highlights the potentially lethal complication of halothane anaesthesia in patients with long QTc interval syndrome.

摘要

一名有惊厥病史的4岁失聪女孩在麻醉诱导期间出现多形性室性心动过速。心律失常自行恢复为窦性心律。麻醉后心电图显示QTc间期明显延长（570 - 690毫秒）。失聪、QTc间期延长以及小细胞低色素性贫血确诊为杰韦尔和朗格 - 尼尔森综合征。本病例报告强调了长QTc间期综合征患者接受氟烷麻醉时潜在的致命并发症。