Department of Medicine, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark, NJ 07103, USA.
Sci Transl Med. 2009 Nov 25;1(8):8cm7. doi: 10.1126/scitranslmed.3000372.
Forensic science can be instrumental in providing investigative leads or clues to help identify the perpetrators, and those who are innocent, of a chemical, biological, radiological, or nuclear terrorist attack, as well as identify leads during infectious outbreaks or other public health threats. Because of a need to react quickly in exigent circumstances during which the threat of continued attack persists, methods may be used that are not fully validated. A preliminary validation should be performed to evaluate the acquisition of limited test data to ensure that the interpretation of results remains within the limitations of known performance of the method. If results from a preliminarily validated method are used beyond developing an investigative lead, further validation should be considered to support its reliability for adjudication purposes.
法医学可以为提供调查线索或证据提供帮助，以帮助识别化学、生物、放射性或核恐怖袭击的肇事者和无辜者，并在传染病爆发或其他公共卫生威胁期间识别线索。由于需要在持续存在威胁的紧急情况下迅速做出反应，因此可能会使用尚未完全验证的方法。应进行初步验证，以评估有限测试数据的获取情况，以确保结果的解释仍然在方法已知性能的限制范围内。如果初步验证的方法的结果被用于除了开发调查线索之外的其他用途，则应考虑进一步验证，以支持其在裁决目的方面的可靠性。
