Fed Regist. 2007 Apr 23;72(77):20117-28.
The United States faces serious public health threats from the deliberate use of weapons of mass destruction (WMD)--chemical, biological, radiological, or nuclear (CBRN)--by hostile States or terrorists, and from naturally emerging infectious diseases that have a potential to cause illness on a scale that could adversely impact national security. Effective strategies to prevent, mitigate, and treat the consequences of CBRN threats is an integral component of our national security strategy. To that end, the United States must be able to rapidly develop, stockpile, and deploy effective medical countermeasures to protect the American people. The HHS Public Health Emergency Medical Countermeasures Enterprise (PHEMCE) has taken a holistic, end-to-end approach that considers multiple aspects of the medical countermeasures mission including research, development, acquisition, storage, maintenance, deployment, and guidance for utilization. Phase one of this approach established the HHS PHEMCE Strategy for Chemical, Biological, Radiological, and Nuclear Threats (HHS PHEMCE Strategy). The HHS PHEMCE Strategy, published in the Federal Register on March 20, 2007, described a framework of strategic policy goals and objectives for identifying medical countermeasure requirements and establishing priorities for medical countermeasure evaluation, development and acquisition. These strategic policy goals and objectives were used to establish the Four Pillars upon which this HHS Public Health Emergency Medical Countermeasures Enterprise Implementation Plan (HHS PHEMCE Implementation Plan) is based. The HHS PHEMCE Implementation Plan considers the full spectrum of medical countermeasures-related activities, including research, development, acquisition, storage/maintenance, deployment, and utilization. The HHS PHEMCE Implementation Plan is consistent with the President's Biodefense for the 21st Century and is aligned with the National Strategy for Medical Countermeasures against Weapons of Mass Destruction.
美国面临着来自敌对国家或恐怖分子蓄意使用大规模杀伤性武器（WMD）——化学、生物、放射性或核（CBRN）武器——以及自然出现的、有可能造成大规模疾病从而对国家安全产生不利影响的传染病的严重公共卫生威胁。预防、减轻和治疗CBRN威胁后果的有效战略是我们国家安全战略的一个组成部分。为此，美国必须能够迅速研发、储备和部署有效的医疗对策，以保护美国民众。美国卫生与公众服务部（HHS）的公共卫生应急医疗对策企业（PHEMCE）采取了一种全面的、端到端的方法，该方法考虑了医疗对策任务的多个方面，包括研究、开发、采购、储存、维护、部署以及使用指导。该方法的第一阶段制定了HHS针对化学、生物、放射性和核威胁的PHEMCE战略（HHS PHEMCE战略）。2007年3月20日在《联邦公报》上发布的HHS PHEMCE战略描述了一个战略政策目标框架，用于确定医疗对策需求，并为医疗对策评估、开发和采购确定优先事项。这些战略政策目标被用于确立本HHS公共卫生应急医疗对策企业实施计划（HHS PHEMCE实施计划）所基于的四大支柱。HHS PHEMCE实施计划考虑了与医疗对策相关的所有活动，包括研究、开发、采购、储存/维护、部署和使用。HHS PHEMCE实施计划与总统的《21世纪生物防御》一致，并与《大规模杀伤性武器医疗对策国家战略》保持一致。
