Department of Internal Medicine, University of Kinshasa, DRC.
Diab Vasc Dis Res. 2010 Jan;7(1):28-39. doi: 10.1177/1479164109346362. Epub 2009 Oct 28.
The first objective of this study was to determine the baseline prevalence of metabolic syndrome and its individual components using the NCEP-R/ATPIII criteria, IDF criteria for Europe, and IDF criteria for Africa: waist circumference of at least 94 cm for men and women. The second objective was to investigate the incidence and the determinants of type 2 diabetes in a prospective cohort of 807 non-diabetic Central Africans aged >or= 40 years from December 2004 to September 2008. During 3,156 person-years of median follow up, there were 93 type 2 diabetes cases (11.5%), corresponding to an incidence of 29 (95% CI 15-43) per 1,000 person-years. The independent predictors of incident type 2 diabetes were age >or= 45 years, physical inactivity, non-diabetic hyperglycaemia and metabolic syndrome regardless of criteria used. In conclusion, urgent prevention strategies are needed to curb the type 2 diabetes epidemic in Africa.
本研究的首要目标是使用 NCEP-R/ATPIII 标准、欧洲 IDF 标准和非洲 IDF 标准（男性腰围至少 94 厘米，女性腰围至少 80 厘米），确定代谢综合征及其各个组成部分的基线患病率。第二项目标是在 2004 年 12 月至 2008 年 9 月期间，对来自中非的 807 名年龄大于等于 40 岁的非糖尿病成年人群进行前瞻性队列研究，以调查 2 型糖尿病的发病率及其决定因素。在 3156 人年的中位随访期间，有 93 例 2 型糖尿病患者（11.5%），相当于每 1000 人年有 29 例（95%CI15-43）。2 型糖尿病的独立预测因素是年龄大于等于 45 岁、体力活动不足、非糖尿病性高血糖和代谢综合征，无论使用何种标准。总之，需要采取紧急预防策略来遏制非洲的 2 型糖尿病流行。
Zotero 插件