Mechanical and Aerospace Engineering, Illinois Institute of Technology, Chicago, Illinois 60616, USA.
Chaos. 2010 Mar;20(1):017512. doi: 10.1063/1.3272780.
Important progress has been achieved in recent years in simulating the fluid-structure interaction around cardiac valves. An important step in making these computational tools useful to clinical practice is the development of postprocessing techniques to extract clinically relevant information from these simulations. This work focuses on flow through the aortic valve and illustrates how the computation of Lagrangian coherent structures can be used to improve insight into the transport mechanics of the flow downstream of the valve, toward the goal of aiding clinical decision making and the understanding of pathophysiology.
近年来,在模拟心脏瓣膜周围的流固耦合方面取得了重要进展。使这些计算工具对临床实践有用的一个重要步骤是开发后处理技术,以便从这些模拟中提取临床相关信息。这项工作侧重于主动脉瓣的流动,并说明了如何使用拉格朗日相干结构的计算来提高对瓣膜下游流动传输力学的认识,以帮助临床决策和理解病理生理学为目标。