机械心脏瓣膜模拟的数值方法综述及血栓形成的可能性。
Review of numerical methods for simulation of mechanical heart valves and the potential for blood clotting.
机构信息
Department of Aerospace Engineering, Faculty of Engineering, Universiti Putra Malaysia, 43400, Serdang, Selangor, Malaysia.
Faculty of Mechanical Engineering, Universiti Teknikal Malaysia Melaka, 76100, Durian Tunggal, Malaysia.
出版信息
Med Biol Eng Comput. 2017 Sep;55(9):1519-1548. doi: 10.1007/s11517-017-1688-9. Epub 2017 Jul 26.
Even though the mechanical heart valve (MHV) has been used routinely in clinical practice for over 60 years, the occurrence of serious complications such as blood clotting remains to be elucidated. This paper reviews the progress that has been made over the years in terms of numerical simulation method and the contribution of abnormal flow toward blood clotting from MHVs in the aortic position. It is believed that this review would likely be of interest to some readers in various disciplines, such as engineers, scientists, mathematicians and surgeons, to understand the phenomenon of blood clotting in MHVs through computational fluid dynamics.
尽管机械心脏瓣膜（MHV）在临床实践中已经常规应用超过 60 年，但仍需要阐明其发生严重并发症（如血栓形成）的机制。本文综述了近年来在数值模拟方法方面取得的进展，以及主动脉位置 MHV 中异常流动对血栓形成的贡献。相信这篇综述可能会引起不同学科的一些读者的兴趣，如工程师、科学家、数学家和外科医生，以便通过计算流体动力学来了解 MHV 中的血栓形成现象。
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