Department of Nephrology, Ankara Education and Research Hospital, and Department of Pathology, Faculty of Medicine, Ankara University, Ankara, Turkey.
Ren Fail. 2010 Jan;32(3):401-3. doi: 10.3109/08860221003640090.
Familial Mediterranean fever (FMF) is an autosomal recessive genetic disease characterized by recurrent attacks of fever and painful episodes of sterile polyserositis. Kidney involvement may occur as a result of secondary amyloidosis during the course of FMF. Previously, different types of glomerulopathies such as IgM and IgA nephropathy, crescentic glomerulonephritis, diffuse proliferative glomerulonephritis, minimal change disease, and membranoproliferative glomerulonephritis were rarely reported. We herein represent a first case of membranous glomerulonephritis who had complete remission with colchicine treatment in the course of familial Mediterranean fever.
家族性地中海热(FMF)是一种常染色体隐性遗传疾病,其特征是反复发作的发热和无菌性多浆膜炎疼痛发作。在 FMF 病程中,肾脏可能会因继发性淀粉样变性而受累。以前,IgM 和 IgA 肾病、新月体性肾小球肾炎、弥漫性增生性肾小球肾炎、微小病变病和膜增生性肾小球肾炎等不同类型的肾小球疾病很少有报道。本文报告了首例在家族性地中海热过程中用秋水仙碱治疗后完全缓解的膜性肾小球肾炎病例。