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[不明原因发热与秋水仙碱敏感的淀粉样变性:家族性地中海热?]

[Fever of unknown origin and colchicine-sensitive amyloidosis: familial Mediterranean fever?].

作者信息

Schneider W, Wehmeier A

机构信息

Medizinische Klinik und Poliklinik der Universität Düsseldorf.

出版信息

Dtsch Med Wochenschr. 1989 Jun 16;114(24):951-4. doi: 10.1055/s-2008-1066699.

Abstract

A 39-year-old man who had for 20 years suffered from recurrent fever, abdominal pain and joint pains was diagnosed to have generalized amyloidosis type AA. Suspected of having familial mediterranean fever (FMF) he was treated with colchicine, 2 mg daily. Within four years the fever bouts became milder and the amyloidosis no longer progressed. Since the patient was a foundling it was impossible to prove FMF, despite the typical signs and the successful treatment.

摘要

一名39岁男性,反复发热、腹痛和关节疼痛20年,被诊断为AA型全身性淀粉样变性。怀疑患有家族性地中海热(FMF),他接受了秋水仙碱治疗,每日2毫克。四年内,发热发作变得较轻,淀粉样变性不再进展。由于该患者是弃婴,尽管有典型症状且治疗成功,但仍无法证实患有FMF。

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