Singh S, de Trafford J C, Baskerville P A, Roberts V C
Department of Medical Physics and Medical Engineering, King's College School of Medicine and Dentistry, Dulwich Hospital, London, U.K.
Eur J Vasc Surg. 1991 Apr;5(2):199-203. doi: 10.1016/s0950-821x(05)80688-7.
This study evaluated the use of a high frequency A-mode ultrasound scanner (CUTECH DM70) for monitoring the digital artery vasospasm of Raynaud's Phenomenon (RP). The technique was evaluated on 12 RP patients and 12 age and sex matched controls. The diameter of a single digital artery was measured in these subjects over a range of finger temperatures between 14-35 degrees C. The reproducibility of the measurements was assessed by repeating the procedure in two subjects (a control and an RP patient) on 5 separate days. The results confirmed that the technique is reproducible and monitored vasospasm occurring in all 12 RP patients. In the temperature range tested, none of the controls developed digital artery vasospasm. At finger temperatures greater than 25 degrees C the response to thermal stimuli of the digital arteries in RP patients and controls was similar. However, at temperatures less than 25 degrees C a marked vasoconstriction leading to complete digital artery closure was seen in the RP patients and not in the controls. This technique may prove useful in monitoring RP patients.
本研究评估了使用高频A型超声扫描仪(CUTECH DM70)监测雷诺现象(RP)患者指动脉血管痉挛的情况。该技术在12例RP患者以及12名年龄和性别相匹配的对照者身上进行了评估。在这些受试者中,于14至35摄氏度的一系列手指温度范围内测量单一指动脉的直径。通过在5个不同日期对两名受试者(一名对照者和一名RP患者)重复该操作来评估测量的可重复性。结果证实该技术具有可重复性,并且监测到了所有12例RP患者出现的血管痉挛。在测试的温度范围内,对照者均未发生指动脉血管痉挛。在手指温度高于25摄氏度时,RP患者和对照者的指动脉对热刺激的反应相似。然而,在温度低于25摄氏度时,RP患者出现了导致指动脉完全闭合的明显血管收缩,而对照者未出现。该技术可能在监测RP患者方面证明有用。