Dimitrakopoulos Ioannis, Ntomouchtsis Aris, Iordanidis Fotis
University Clinic of Oral and Maxillofacial Surgery, G. Papanikolaou General Hospital, P. Mela 28, 546 22 Thessaloniki, Greece.
Oral Maxillofac Surg. 2011 Jun;15(2):121-5. doi: 10.1007/s10006-010-0218-9.
Carcinoma of the uterine cervix is the fourth commonest malignant tumor in women. The disease spreads into the surrounding tissues by direct infiltration whereas spread by hematogenous dissemination is relatively unusual, and most commonly involves the lung, bone, and liver. The involvement of oral and maxillofacial region is extremely rare in gynecological cancer.
In this paper, we present an unusual case of a metastatic squamous cell carcinoma originating in the infratemporal fossa of a 37-year-old woman who had underwent a subtotal hysterectomy, for squamous cell carcinoma of the cervix, 22 months earlier. A whole-body CT scan revealed a mass of enlarged lymph nodes in the mediastinum as well. The patient, who had presented for evaluation of a rapidly increasing trismus associated with deep intermittent facial pain and temporal swelling had initially been treated for a TMJ dysfunction and later for an infratemporal fossa abscess for long before a definite diagnosis was made. A high index of suspicion is possible to make an early diagnosis, which when coupled with an aggressive management can improve survival and quality of life.
子宫颈癌是女性中第四常见的恶性肿瘤。该疾病通过直接浸润扩散到周围组织,而血行播散相对少见,最常累及肺、骨和肝。在妇科癌症中,口腔颌面部受累极为罕见。
在本文中,我们呈现了一例不寻常的转移性鳞状细胞癌病例,该病例起源于一名37岁女性的颞下窝,该女性在22个月前因宫颈鳞状细胞癌接受了子宫次全切除术。全身CT扫描还显示纵隔有肿大淋巴结。该患者因与深部间歇性面部疼痛和颞部肿胀相关的张口受限迅速加重前来评估,最初被诊断为颞下颌关节功能障碍,后来又被诊断为颞下窝脓肿,在确诊之前已经接受了很长时间的治疗。高度怀疑有助于早期诊断,早期诊断加上积极的治疗可以提高生存率和生活质量。