Mustafa M S, Al-Nuaim L, Inayat-Ur-Rahman N
Department of Obstetrics and Gynaecology, King Khalid University Hospital, Riyadh 11472, Saudi Arabia.
Gynecol Oncol. 2001 Apr;81(1):105-9. doi: 10.1006/gyno.2000.6038.
The aim of this study is to report a rare case of scalp and cranial bone metastasis of endometrial carcinoma and review the literature.
We report a 45-year-old multiparous woman with FIGO Stage 1A Grade II endometrial adenocarcinoma who presented 3 years following total abdominal hysterectomy and bilateral salpingo-oophorectomy with scalp and cranial bone metastasis. Similar cases in the literature are reviewed.
The patient metastatic workup revealed local, distant, scalp, and cranial bone metastasis. She died within 6 months. The poor prognosis is similar to that of six other cases reviewed.
Scalp and cranial bone metastasis following endometrial carcinoma is extremely rare. It is a reflection of a widely disseminated disease and poor prognosis. However, single bone metastasis has a better postmetastatic survival with the help of local radiotherapy than scalp and multiple bone metastasis.
本研究旨在报告一例罕见的子宫内膜癌头皮及颅骨转移病例并复习相关文献。
我们报告一名45岁经产妇，患有国际妇产科联盟（FIGO）1A期II级子宫内膜腺癌，在全腹子宫切除术及双侧输卵管卵巢切除术后3年出现头皮及颅骨转移。对文献中的类似病例进行了复习。
患者的转移检查显示存在局部、远处、头皮及颅骨转移。她在6个月内死亡。其预后不良与其他6例复习病例相似。
子宫内膜癌后发生头皮及颅骨转移极为罕见。这反映了疾病广泛播散且预后不良。然而，单发性骨转移在局部放疗的帮助下，转移后的生存期比头皮及多发性骨转移要好。
