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一例因误食热敷袋导致高钙血症和胃坏死的病例。

A case of hypercalcemia and gastric necrosis from hot pack ingestion.

作者信息

Padmanabhan Pradeep, Spiller Henry A, Bosse George M

机构信息

Department of Pediatrics, Division of Pediatric Emergency Medicine, Kosair Children's Hospital, University of Louisville, Louisville, KY 40202, USA.

出版信息

J Med Toxicol. 2010 Jun;6(2):139-42. doi: 10.1007/s13181-010-0063-0.

Abstract

Hot packs (instant hot compresses) are frequently used to relieve pain. We report a patient who had significant complications from ingestion of a hot pack containing calcium salts. A 35-year-old male swallowed three hot packs, and developed hematemesis, severe abdominal pain, and hypercalcemia (21.1 mg/dl). He developed diffuse gastric necrosis requiring gastrectomy and colonic interposition. Hypercalcemia was treated with intravenous fluids, pamidronate, and calcitonin. A Medline search revealed no prior report on hot pack ingestion though ingestion of calcium salts has been reported. Hot packs can potentially cause significant injury both from an exothermic reaction and hypercalcemia. Ingestions of calcium salts can result in necrosis of the stomach. Management includes aggressive treatment of hypercalcemia, supportive care and upper gastrointestinal endoscopy.

摘要

热敷袋(即时热敷)常用于缓解疼痛。我们报告了一名因摄入含钙盐的热敷袋而出现严重并发症的患者。一名35岁男性吞下了三个热敷袋,随后出现呕血、严重腹痛和高钙血症(21.1mg/dl)。他发生了弥漫性胃坏死,需要进行胃切除术和结肠间置术。高钙血症通过静脉补液、帕米膦酸盐和降钙素进行治疗。医学文献检索显示,尽管已有摄入钙盐的报告,但此前尚无关于摄入热敷袋的报道。热敷袋可能因放热反应和高钙血症而造成严重损伤。摄入钙盐可导致胃坏死。治疗包括积极治疗高钙血症、支持治疗和上消化道内镜检查。

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本文引用的文献

1
Pamidronate treatment of hypercalcemia caused by vitamin D toxicity.帕米膦酸盐治疗维生素D中毒引起的高钙血症。
J Pediatr Endocrinol Metab. 2007 Nov;20(11):1241-8. doi: 10.1515/jpem.2007.20.11.1241.
3
Massive strontium ferrite ingestion without acute toxicity.大量摄入锶铁氧体但无急性毒性。
Basic Clin Pharmacol Toxicol. 2006 Nov;99(5):358-9. doi: 10.1111/j.1742-7843.2006.pto_566.x.

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