Gong Hyun Sik, Cho Jae Hwan, Roh Young Hak, Chung Moon Sang, Baek Goo Hyun
Department of Orthopaedics, Hand and Upper Extremity Service, Seoul National University Bundang Hospital, Seongnam, Korea.
J Hand Surg Am. 2010 Jun;35(6):999-1002. doi: 10.1016/j.jhsa.2010.02.027. Epub 2010 Apr 7.
Imiquimod 5% cream is known as an alternative treatment option for squamous cell carcinoma in situ (SCCIS), frequently termed Bowen's disease. Although imiquimod cream has been reported by many authors to treat SCCIS successfully, its efficacy and safety have not been fully established. The authors experienced a case in which ray amputation was necessary because of bone invasion by SCCIS in a finger being treated with imiquimod cream.
5%咪喹莫特乳膏是原位鳞状细胞癌(SCCIS,常称为鲍温病)的一种替代治疗选择。尽管许多作者报告咪喹莫特乳膏成功治疗了SCCIS,但其疗效和安全性尚未完全确立。作者遇到一例在用咪喹莫特乳膏治疗手指SCCIS时,因肿瘤侵犯骨质而需要进行射线截肢的病例。