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Molecular and alternative methods for diagnosis of acute myeloid leukemia with mutated NPM1: flexibility may help.

作者信息

Falini Brunangelo, Martelli Maria Paola, Pileri Stefano A, Mecucci Cristina

出版信息

Haematologica. 2010 Apr;95(4):529-34. doi: 10.3324/haematol.2009.017822.

Abstract
摘要

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本文引用的文献

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Strikingly different molecular relapse kinetics in NPM1c, PML-RARA, RUNX1-RUNX1T1, and CBFB-MYH11 acute myeloid leukemias.
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Minimal residual disease levels assessed by NPM1 mutation-specific RQ-PCR provide important prognostic information in AML.
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