[一例伴有淋巴结转移的十二指肠神经节细胞性副神经节瘤]

[A case of duodenal gangliocytic paraganglioma with lymph node metastasis].

作者信息

Saito Junko, Hirata Nobuto, Furuzono Mitoshi, Nakaji So, Inase Masami, Nagano Hiroshi, Iwata Maiko, Tochitani Shinako, Fukatsu Kazuhiro, Fujii Hiroyuki, Ishii Eiji, Kataoka Junro, Mikata Rintaro, Masuya Yoshio, Ito Hiroshi, Ohmori Jun, Wakasugi Satoshi, Ebara Masaaki, Hoshi Kazuei

机构信息

Department of Gastroenterology, Kameda Medical Center, Japan.

出版信息

Nihon Shokakibyo Gakkai Zasshi. 2010 Apr;107(4):639-48.

PMID:20379099

Abstract

A 28-year-old man complained of tarry stool. A series of examinations showed a submucosal tumor with bleeding at the papilla of Vater and a swollen # 17b lymph node, both of which indicated a hypervascular tumor. The pathological findings of the enucleated tumor specimens revealed gangliocytic paraganglioma with metastasis to the # 17b lymph node. Additional pancreaticoduodenectomy revealed another # 17b lymph node metastasis 7-mm in diameter. Although the majority of gangliocytic paragangliomas are benign, 7% of reported cases have lymph node metastases, as shown in the present case. These findings are important in treating patients with gangliocytic paraganglioma.

摘要

一名28岁男性主诉排柏油样便。一系列检查显示在 Vater 乳头处有一个伴有出血的黏膜下肿瘤以及一个肿大的17b号淋巴结，两者均提示为富血管性肿瘤。摘除的肿瘤标本病理检查结果显示为神经节细胞性副神经节瘤，伴有17b号淋巴结转移。进一步的胰十二指肠切除术发现了另一处直径7毫米的17b号淋巴结转移灶。尽管大多数神经节细胞性副神经节瘤是良性的，但如本病例所示，报告病例中有7%发生淋巴结转移。这些发现对于治疗神经节细胞性副神经节瘤患者具有重要意义。