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Dynamics of adherence junctions during early stages of epithelial-mesenchymal transition: possible mechanisms of tube and alveolus formation in ontogeny.

作者信息

Rubtsova S N, Vasiliev Yu M

机构信息

Belozersky Institute of Physico-Chemical Biology, Moscow State University, Moscow, 119992 Russia.

出版信息

Dokl Biol Sci. 2010 Jan-Feb;430:64-6. doi: 10.1134/s0012496610010217.

DOI:10.1134/s0012496610010217
PMID:20380185
Abstract
摘要

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Dynamics of adherence junctions during early stages of epithelial-mesenchymal transition: possible mechanisms of tube and alveolus formation in ontogeny.上皮-间质转化早期阶段黏着连接的动态变化：个体发育中管和肺泡形成的可能机制。
Dokl Biol Sci. 2010 Jan-Feb;430:64-6. doi: 10.1134/s0012496610010217.
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Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly.Ras对丝裂原活化蛋白激酶（MAP激酶）和磷脂酰肌醇3激酶的激活是肝细胞生长因子/分散因子诱导黏附连接解体所必需的。
Mol Biol Cell. 1998 Aug;9(8):2185-200. doi: 10.1091/mbc.9.8.2185.

本文引用的文献

1
Basal-to-apical cadherin flow at cell junctions.细胞连接处从基底到顶端的钙黏蛋白流动。
Nat Cell Biol. 2007 Jan;9(1):92-8. doi: 10.1038/ncb1520. Epub 2006 Dec 10.
2
Integrin-dependent actomyosin contraction regulates epithelial cell scattering.整合素依赖性肌动球蛋白收缩调节上皮细胞散射。
J Cell Biol. 2005 Oct 10;171(1):153-64. doi: 10.1083/jcb.200506152.
3
Leaving the neighborhood: molecular mechanisms involved during epithelial-mesenchymal transition.离开邻域：上皮-间质转化过程中涉及的分子机制。
Bioessays. 2001 Oct;23(10):912-23. doi: 10.1002/bies.1132.
4
Myosin-dependent contractile activity of the actin cytoskeleton modulates the spatial organization of cell-cell contacts in cultured epitheliocytes.肌动蛋白细胞骨架的肌球蛋白依赖性收缩活动调节培养上皮细胞中细胞间接触的空间组织。
Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9666-70. doi: 10.1073/pnas.96.17.9666.
5
Morphogenetic effects of neuregulin (neu differentiation factor) in cultured epithelial cells.神经调节蛋白（神经分化因子）对培养上皮细胞的形态发生作用。
Mol Biol Cell. 1998 Nov;9(11):3195-209. doi: 10.1091/mbc.9.11.3195.
6
Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells.Ras、Rac和Rho对MDCK细胞中散射因子/肝细胞生长因子反应的调节
Mol Cell Biol. 1995 Feb;15(2):1110-22. doi: 10.1128/MCB.15.2.1110.
7
The role of the microtubular system in the cell response to HGF/SF.微管系统在细胞对肝细胞生长因子/散射因子反应中的作用。
J Cell Sci. 1995 Apr;108 ( Pt 4):1659-67. doi: 10.1242/jcs.108.4.1659.
8
Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement.分散因子的纯化，一种由成纤维细胞产生的可调节上皮细胞相互作用和运动的碱性蛋白。
Proc Natl Acad Sci U S A. 1989 Aug;86(15):5844-8. doi: 10.1073/pnas.86.15.5844.
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Effect of scatter factor on motility of epithelial cells and fibroblasts.
J Cell Physiol. 1989 Jun;139(3):565-9. doi: 10.1002/jcp.1041390316.
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Induction of epithelial tubular morphogenesis in vitro by fibroblast-derived soluble factors.
Cell. 1991 Aug 23;66(4):697-711. doi: 10.1016/0092-8674(91)90115-f.