Department of Neurology, Leiden University Medical Center (LUMC), Leiden, The Netherlands.
Autoimmunity. 2010 Aug;43(5-6):344-52. doi: 10.3109/08916931003602130.
Myasthenia gravis and myasthenic syndromes are diseases of the neuromuscular junction. Autoantibodies and toxins to or mutations in one of the synaptic proteins are the main causes of dysfunction. Myasthenic phenotypes can be classified according to the basic aetiological mechanisms or divided depending on the clinical phenotype.
重症肌无力和肌无力综合征是神经肌肉接头疾病。自身抗体和毒素或突触蛋白之一的突变是功能障碍的主要原因。肌无力表型可以根据基本病因机制进行分类,也可以根据临床表型进行划分。